miRNA (microRNA) is a class of endogenous small non-coding RNA, with a length of about 17-25 bp, which can bind to target mRNA specifically, cause target mRNA degradation or inhibit its translation, and thus participate in the post-transcriptional regulation of genes. miRNA participates in multiple gene regulation pathways, from embryonic development, viral defense, hematopoiesis, organ formation, cell proliferation and apoptosis, lipid metabolism to tumor growth. miRNA plays an important role in a series of physiological and pathological processes, and is screened as a reliable disease biomarker. In addition, scientists are currently trying to change the function of miRNA, develop new mechanisms of action, such as regulating genomic expression, so that it may become an effective intervention and treatment for diseases.
Service Details
miRNA Service
S/N | Services | Specification |
PRmi001 | Regular miRNA mimics synthesis | 2.5nmol 100nmol |
PRmiT001 | Regular miRNA Inhibitor synthesis | 2.5nmol 10nmol 100nmol |
PRmia001 | Modified miRNA agomir synthesis | 2.5nmol 5nmol 10nmol |
PRmia201 | Modified miRNA antagomir synthesis | 2.5nmol 100nmol |
PRmip101 | pre-miRNA mimic | 2.5nmol |
miRNA Library
S/N | Services | Specification |
PRmi301 | homo miRNA library A library(5p) | 0.25nmol/gene number*120RMB (Order from 100 miRNAs) |
PRmi302 | homo miRNA library B library(3p) | |
PRmi401 | Mus miRNA library A library(5p) | |
PRmi402 | Mus miRNA library B library(3p) | |
PRmi501 | Rat miRNA library A library(5p) | |
PRmi502 | Rat miRNA library B library(3p) | |
PRmi601 | Dual fluorescein validated target screening service | 3-choice 1 target screening validation service WB and qPCR |
PRmi701 | Cell function validation services | Each per item |
Ordering Tips
1. Customers need to provide all miRNA mimic, inhibitor, precursor of human, mouse and rat in the latest miRBase database, specific ID information (if mature miRNA is required, it needs to be clearly noted whether to do 3p or 5p);
2. If other species of miRNA mimic, inhibitor, precursor and mature miRNA not included in miRBase are customized, customers need to provide specific sequence information;
3. The minimum order quantity is 5 nmol, and the minimum order quantity of modified customized miRNA is 5 nmol.