Custom RNA Oligos

Features

  • Scalable Capacity

    • From discovery research to preclinical validation, your RNA needs may change—but your supplier doesn't have to. We support synthesis up to gram scale and 120 nt, including multiple modifications on a single oligo.

  • High Quality, Low Endotoxin

    • Don't worry about sequence mismatches and incomplete capping, our self-designed synthesis platforms and optimized protocols ensure high-fidelity synthesis and 100% accurate sequence delivery

    • Tired of poor transfection or unexpected toxicity? Our DSL, HPLC, and DHPLC purification options minimize impurities and deliver RNA with purity levels exceeding 98%.

  • Professional Technological Team

    • New to RNA or need support for your specific project? Just tell us your target gene, species, and application, our team with 20+ years of RNA experience will handle the rest of this process, including sequence design, synthesis, and even the downstream protocols if needed.


Service Details

BiOligo provides single-stranded and duplexed RNA synthesis (10–120 nt), including sgRNA, siRNA, miRNA, and crRNA, with customizable options for different experimental needs.

Product NamePurificationQuantityQCLead Time
(Bussiness Day)
RNA SynthesisDSL / HPLC / DHPLCUp to g scale100% MS & HPLC7 ~ 10



Modification Types

Fluorescent Group

FAM, BF553, BF647, BF675, BF750, BECU_BF 650, HEX, BF530, ROX, TET, BF390, BF425, BF595, BF633, BF648, BF680, BF405, BF488, JOE, BF549, TAMRA, BF649, BF690, Dylight 755, BF592, Methylene Blue

Quenching Group

BHQ-0, BHQ-1, BHQ-2, BHQ-3, MGB, Eclipse, Dabcyl, SQ1, SQ2

Special Bases

LNA-A/C/G/T, RNA-A/C/G/U, DNA-A/C/G/T, ddC, 2’-O-Methyl, 2’-MOE, 2’-F, 5-Me-dC, rl, dl

Linkers

Spacer 9, Spacer 18, Spacer C3, Spacer C6

Phosphorylation Modifications

PHOS

Thiophosphate Modifications

Phosphorothioate

*For other modifications or larger-scale RNA oligo requests, please contact our sales team: hernando.tang@bioligo.com