——Fast, high-purity, and professional oligonucleotide synthesis solutions to accelerate nucleic acid drug development.
With 15 years of expertise in nucleic acid synthesis, BiOligo leverages a mature oligonucleotide chemistry platform and comprehensive quality control system to provide high-purity, low-endotoxin oligonucleotide products from nmol to kilogram scale for nucleic acid drug development from CRO to CDMO, enabling end-to-end support for small nucleic acid therapeutics development.
Product Advantages
Product Types
Custom Synthesis
siRNA miRNA ASO Aptamer sgRNA
Nucleic Acid Drug Intermediates
Modification and Conjugation Platforms
Modification Types
Chemical modification of nucleotides can improve target specificity, enhance nuclease resistance, and reduce immunogenicity. With 15+ years of specialized oligonucleotide synthesis experience and proprietary modification technologies, BiOligo provides access to 200+ chemical modifications across sugar, backbone, base, and labeling categories. These modifications can be introduced at different positions and combined flexibly to meet diverse structural design requirements.
Conjugation Types
BiOligo provides diverse molecular conjugation strategies, enabling oligonucleotide conjugation with antibodies, peptides, small molecules, and other functional moieties to support various conjugation approaches.
Quality Control
BiOligo provides 100+ quality control methods covering structural characterization, purity analysis, water content, endotoxin testing, osmolality, free acid content, sodium ion quantification, viscosity analysis, trace pH measurement, and more. Customized QC solutions can be tailored based on modification types, modification stereochemistry, and development stage requirements.
