——Ultra-low endotoxin, super-high purity, and scalable oligonucleotide synthesis solutions for RNAi therapeutics development.
With over 15 years of experience in oligonucleotide synthesis, BiOligo leverages a superior oligonucleotide chemistry platform and comprehensive quality control system to provide super-high purity oligonucleotide products with ultra-low endotoxin levels from nmol to kilogram scale. Supporting RNAi therapeutics development from CRO to CDMO，BiOligo enables end-to-end support throughout the development lifecycle.
Product Advantages
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Product List
Custom Synthesis
siRNA ASO miRNA Aptamer sgRNA
- Off-the-Shelf Products
Modification and Conjugation Platforms
- Modification Capabilities
Supports over 200+ chemical modifications, including MOE, 2′-O-Methyl, 2′-Fluoro, phosphorothioate (PS), and more.
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Conjugation Types Capabilities
BiOligo provides diverse molecular conjugation strategies, enabling oligonucleotide conjugation with antibodies, peptides, small molecules, and other functional moieties to support various conjugation approaches.
Quality Control
BiOligo provides 100+ quality control methods covering structural characterization, purity analysis, water content, endotoxin testing, osmolality, free acid content, sodium ion quantification, viscosity analysis, trace pH measurement, and more. Customized QC solutions can be tailored based on modification types, modification stereochemistry, and development stage requirements.
