Features

Scalable Capacity
- From discovery research to preclinical validation, your RNA needs may change—but your supplier doesn't have to. We support synthesis up to gram scale and 120 nt, including multiple modifications on a single oligo.
High Quality, Low Endotoxin
- Don't worry about sequence mismatches and incomplete capping, our self-designed synthesis platforms and optimized protocols ensure high-fidelity synthesis and 100% accurate sequence delivery
- Tired of poor transfection or unexpected toxicity? Our DSL, HPLC, and DHPLC purification options minimize impurities and deliver RNA with purity levels exceeding 98%.
Professional Technological Team
- New to RNA or need support for your specific project? Just tell us your target gene, species, and application, our team with 20+ years of RNA experience will handle the rest of this process, including sequence design, synthesis, and even the downstream protocols if needed.

Service Details

BiOligo provides single-stranded and duplexed RNA synthesis (10–120 nt), including sgRNA, siRNA, miRNA, and crRNA, with customizable options for different experimental needs.

Product Name	Purification	Quantity	QC	Lead Time (Bussiness Day)
RNA Synthesis	DSL / HPLC / DHPLC	Up to g scale	100% MS & HPLC	7 ~ 10

Modification Types

Fluorescent Group	FAM, BF553, BF647, BF675, BF750, BECU_BF 650, HEX, BF530, ROX, TET, BF390, BF425, BF595, BF633, BF648, BF680, BF405, BF488, JOE, BF549, TAMRA, BF649, BF690, Dylight 755, BF592, Methylene Blue
Quenching Group	BHQ-0, BHQ-1, BHQ-2, BHQ-3, MGB, Eclipse, Dabcyl, SQ1, SQ2
Special Bases	LNA-A/C/G/T, RNA-A/C/G/U, DNA-A/C/G/T, ddC, 2’-O-Methyl, 2’-MOE, 2’-F, 5-Me-dC, rl, dl
Linkers	Spacer 9, Spacer 18, Spacer C3, Spacer C6
Phosphorylation Modifications	PHOS
Thiophosphate Modifications	Phosphorothioate

*For other modifications or larger-scale RNA oligo requests, please contact our sales team: hernando.tang@bioligo.com