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Custom RNA Oligos

Scalable Capacity

  • From discovery research to preclinical validation, your RNA needs may change — but your supplier doesn't have to. We support synthesis up to gram scale and 120 nt, including multiple modifications on a single oligo.

High Quality, Low Endotoxin  

  • Don't worry about sequence mismatches and incomplete capping, our self-designed synthesis platforms and optimized protocols ensure high-fidelity synthesis and 100% accurate sequence delivery

  • Tired of poor transfection or unexpected toxicity? Our DSL, HPLC, and DHPLC purification options minimize impurities and deliver RNA with purity levels exceeding 98%.

Professional Technical Team

  • New to RNA or need support for your specific project? Just tell us your target gene, species, and application. Our team, backed by over 20 years of RNA experience, will handle the entire process, including sequence design, synthesis, and any required downstream protocols.

Service Details

BiOligo offers single-stranded and duplexed RNA synthesis (10–120 nt), including sgRNA, siRNA, miRNA, and crRNA, with customizable options tailored to various experimental needs.

Product Name Purification Quantity QC Lead Time
(Business Day)
RNA Synthesis DSL / HPLC / DHPLC Up to g scale 100% MS & HPLC 7 ~ 10

Modification Types

Fluorescent Group

FAM, BF553, BF647, BF675, BF750, BECU_BF 650, HEX, BF530, ROX, TET, BF390, BF425, BF595, BF633, BF648, BF680, BF405, BF488, JOE, BF549, TAMRA, BF649, BF690, Dylight 755, BF592, Methylene Blue

Quenching Group

BHQ-0, BHQ-1, BHQ-2, BHQ-3, MGB, Eclipse, Dabcyl, SQ1, SQ2

Special Bases

LNA-A/C/G/T, RNA-A/C/G/U, DNA-A/C/G/T, ddC, 2’-O-Methyl, 2’-MOE, 2’-F, 5-Me-dC, rl, dl

Linkers

Spacer 9, Spacer 18, Spacer C3, Spacer C6

Phosphorylation Modifications

PHOS

Thiophosphate Modifications

Phosphorothioate

*For other modifications or larger-scale RNA oligo requests, don't hesitate to get in touch with our sales team: hernando.tang@bioligo.com