Hybridization Capture

BiOligo offers a full-process, highly customized hybridization capture solution, covering every critical step from blockers and hybridization capture kits to panel design and synthesis. Our workflow is designed to meet the demanding requirements of both research and clinical applications, ensuring high coverage, high specificity, and outstanding consistency.
 
Our high-performance blockers are fully compatible with Illumina (TruSeq/Nextera) and UMI libraries. They effectively reduce non-specific binding and enhance capture efficiency, demonstrating performance comparable to leading international brands. In terms of hybridization capture kits, BiOligo products maintain excellent uniformity, coverage, and data quality, even under 1–12 sample multiplex conditions, supporting a wide range of downstream applications. For more tailored research needs, we also offer custom design and synthesis services for hybridization capture panels, including difficult targets such as high-GC or highly complex regions—with verified on-target coverage up to 100%.
 
With in-house design expertise and synthesis platforms, BiOligo empowers users to build more accurate and efficient target enrichment systems, providing a solid foundation for studies in oncology, genetic disorders, and pathogen detection.