Custom DNA Oligos

BiOligo brings over 15 years of oligo synthesis experience to every project. We offer comprehensive support and fully customized solutions. Whether you need specialized primers, probes, or other oligonucleotide products, we will work closely with you to deliver exactly what your experiments demand.

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Features

High Quality, Scalable Capacity  
  • Extremely low batch-to-batch variance (CV≤ 0.44%), supporting large-scale commercial use of your applications

  • Fully scalable capacity up to mmol scale, catering to all your development and production needs

Hassle-free, Normalized Delivery  

  • You get exact, precise final yield that you order for - so you can plan your batch production much more easily, manage inventory without unexpected shortage, and set budgeting targets accurately

  • It also helps to skip tedious quantification and normalization work on your own, so that you can focus your time and energy on the most important work - bring your applications to the world 

High Purity & Extra Long Oligo Best Solutions  

  • When you want high purity oligos but those available are too expensive? Try out our DSL, PAGE, HPLC and DHPLC solutions with industry-leading performance and best quotations

    • 100% Mass Spectrometry verified, molecular weight bias ≤ 0.05%

    • Real-world testing data for samples > 1000 OD: purity ~98.8%, covariance < 0.44%

  • Thinking about applications with >100bp oligos? We offer high quality, affordable oligos up to 160 bp that suit your needs

Fast Turnaround, 24/7 Support  

  • Order worldwide, and we will produce and deliver it to you within 5 business days (for large orders > umol or extra long oligos > 100bp, lead time < 10 business days)
  • Got a question? Check out our 24/7 support team who are dedicated to help you

 

 

Modification Choices

BiOligo offers more than 200 types of oligonucleotide modifications, e.g., fluorophores, quenchers, chemical groups, special bases, spacers, and phosphorylates.

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They can be modified at different positions per your requirements, e.g., 5’ end, 3’end, double-end, middle and special base modifications, etc.

 

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Purification Choices

Purification

Method

Purity

Characteristics

DSL

C18 column desalination

>70%

Advantages: High throughput, short period, low cost;

Disadvantages: Difficult to remove shorter fragments;

Application: Suitable for short-chain or non-high purity primers.

UPAGE

OPC column purification

>80%

Advantages: High throughput, short period, high cost performance;

Disadvantages: Efficiency to remove fragments above 45 nt steadily decreases;

Suggestion: Suitable for primers shorter than 45 nt.

PAGE

Polyacrylamide gel electrophoresis

>90%

Advantages: Removes synthesized   short-chain primers, good effect for long-chain primers (>45 nt) or   primers with high quality requirements, with purity over 90%;

Disadvantages: Low capacity, complex operation.

HPLC

High-performance liquid chromatography

>95%

Advantages: High purity (over 95%) and sensitivity;

Disadvantages: Higher cost;

Suggestions: Suitable for primers shorter than 40 nt, good purification effect for primers with special modifications.

DHPLC

Double purification combination

>98%

Suggestion: Suitable for primers and probes with special requirements.

 

 

 

 

Delivery Formats

Shipped dry, or resuspended to your specifications. 

Lyophilized Powder
Liquid Solution

 

 

 

 

 

Pack Formats

Products can be packaged in centrifuge tubes, screw-cap vials, or 96-well plates.

1.5 mL / 2 mL / 5 mL / 50 mL centrifuge tubes or screw-cap vials
96-well plates