gRNA

Guide RNAs (gRNAs) are essential components of the CRISPR-Cas9 system, directing Cas9 to specific genomic loci to introduce targeted gene edits. High-quality gRNA is critical for achieving precise, efficient, and reproducible genome modifications.
BiOligo offers chemically synthesized single-stranded gRNA products that simplify your workflow and improve editing outcomes.

Precise and efficient design

We utilize our proprietary algorithm to optimize gRNA sequences. This approach targets functionally important coding regions, leading to maximized frameshift mutation rates and highly efficient gene knockouts.

Superior Workflow Efficiency

Chemically synthesized single-stranded gRNA (crRNA + tracrRNA) eliminates the need for plasmid construction or in vitro transcription, saving valuable time while delivering higher stability and editing efficiency.

Fast Turnaround

Standard 10 nmol gRNA orders can be delivered within 7 business days, helping you accelerate your genome editing experiments.