Oligo Aptamers
Aptamers are short, single-stranded DNA or RNA oligonucleotides that can bind specific targets — such as proteins, peptides, or small molecules — with high affinity and specificity. They function similarly to antibodies but offer higher stability, easy chemical modification, and reproducible synthesis.
As an experienced oligo manufacturer, BiOligo provides high-quality, customizable aptamer oligos to support your discovery research, diagnostic assay development, and therapeutic innovation. Each aptamer can be provided in various quantities and delivery formats.
Features
- Flexible Design: Custom DNA or RNA aptamers up to 180 nt (longer upon request).
- High Purity: DSL, PAGE and HPLC purification options available.
- Wide Range of Modifications: Biotin, fluorophores, amino, thiol, PEG, spacers, etc.
- Strict Quality Control: Verified by 100% MS and HPLC analysis; additional QC tests available upon request.
- Ready for SELEX or Target Validation: Synthesis suitable for screening or functional assays.
Modification Options
- 5' modifications: Biotin, fluorophore (FAM, Cy5, TAMRA), amino, thiol, etc.
- 3' modifications: Spacer C3, inverted dT, quencher, biotin, etc.
- Internal modifications: dA*, dT*, fluorophore or quencher insertions.
- Backbone modifications: 2'-OMe, 2'-F, phosphorothioate linkage, etc.
Not sure which modification suits your project? Our technical specialists can recommend the best design for your assay or SELEX round.
Applications
- Target binding and screening (SELEX)
- Diagnostic assay development (ELISA, lateral flow, biosensors)
- Therapeutic research and drug delivery
- Biomarker detection and affinity purification
- Functional nucleic acid research
