Stocked Blockers
BiOligo’s high-performance blocking reagents are specially formulated to enhance capture specificity and reduce background noise, ensuring more accurate and reliable sequencing data.
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High Capture Efficiency: Minimizes non-specific hybridization, significantly improving on-target rates.
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Broad Compatibility: Suitable for Illumina (TruSeq/Nextera), MGI platforms, and UMI-tagged libraries.
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Customizable Solutions: Our blocking reagents can be tailored to your specific probe sets, workflows, or target enrichment needs.
By reducing off-target reads and improving signal-to-noise ratios, our blocking reagents help researchers maximize the efficiency of hybrid capture workflows, reduce sequencing costs, and achieve higher confidence in variant calling—particularly important in applications such as cancer panel testing, exome sequencing, and low-frequency mutation detection.
Product Data
High Capture Efficiency
As shown in the figure, BiOligo's capture efficiency outperforms Supplier X and Supplier Y (BiOligo ＞ Supplier X ＞ Supplier Y). This higher efficiency means less raw sequencing data is required to achieve reliable variant detection, which significantly reduces overall sequencing costs. This makes our solution particularly advantageous for cost-sensitive or large-scale projects.
High Coverage
As shown in the figure, BiOligo's hybridization capture solution delivers higher coverage compared to competitor T at a sequencing depth of 100×. This superior coverage—the proportion of target regions successfully sequenced—enables the detection of more variant sites, providing a more comprehensive view of the targeted genomic regions.
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