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miRNA

miRNA (microRNA) is a class of endogenous small non-coding RNA, with a length of about 17-25 bp, which can bind to target mRNA specifically, cause target mRNA degradation or inhibit its translation, and thus participate in the post-transcriptional regulation of genes. miRNA participates in multiple gene regulation pathways, from embryonic development, viral defense, hematopoiesis, organ formation, cell proliferation and apoptosis, lipid metabolism to tumor growth. miRNA plays an important role in a series of physiological and pathological processes, and is screened as a reliable disease biomarker. In addition, scientists are currently trying to change the function of miRNA, develop new mechanisms of action, such as regulating genomic expression, so that it may become an effective intervention and treatment for diseases.




Service Details


miRNA Service

S/N

Services

Specification

PRmi001

Regular miRNA mimics synthesis

2.5nmol
5nmol
10nmol

100nmol
Others

PRmiT001

Regular miRNA Inhibitor synthesis

2.5nmol
5nmol

 10nmol

100nmol
Others

PRmia001

Modified miRNA agomir synthesis

2.5nmol

5nmol

10nmol
100nmol
 Others

PRmia201

Modified miRNA antagomir synthesis

2.5nmol
5nmol
10nmol

100nmol
Others

PRmip101

pre-miRNA mimic

2.5nmol
5nmol
10nmol





miRNA Library

S/N

Services

Specification

PRmi301

homo miRNA library A library(5p)

0.25nmol/gene number*120RMB

(Order from 100 miRNAs)

PRmi302

homo miRNA library B library(3p)


PRmi401

Mus miRNA library A library(5p)


PRmi402

Mus  miRNA library   B library(3p)


PRmi501

Rat miRNA library A library(5p)


PRmi502

Rat miRNA library B library(3p)


PRmi601

Dual fluorescein validated target screening service

3-choice 1 target screening validation service WB and qPCR

PRmi701

Cell function validation services

Each per item




Ordering Tips

1. Customers need to provide all miRNA mimic, inhibitor, precursor of human, mouse and rat in the latest miRBase database, specific ID information (if mature miRNA is required, it needs to be clearly noted whether to do 3p or 5p);

2. If other species of miRNA mimic, inhibitor, precursor and mature miRNA not included in miRBase are customized, customers need to provide specific sequence information;

3. The minimum order quantity is 5 nmol, and the minimum order quantity of modified customized miRNA is 5 nmol.