With over 15 years of expertise in oligonucleotide synthesis, BiOligo provides high-purity oligonucleotides from nmol-scale discovery studies to hundred-gram manufacturing campaigns. Leveraging robust oligonucleotide chemistry platforms and comprehensive quality systems, we support every stage of nucleic acid therapeutic development with integrated synthesis solutions.
Key Advantages
Product Types
Custom Oligonucleotide Synthesis
siRNA miRNA ASO Aptamer sgRNA
Oligonucleotide Therapeutic Intermediates
Modification & Conjugation Platform
Modification Options
Chemical modifications can enhance target specificity, improve nuclease resistance, and reduce immunogenicity. Backed by 15+ years of synthesis expertise and proprietary modification technologies, BiOligo offers over 200 modification chemistries across the sugar, backbone, base, and labeling chemistries.
Our platform supports site-specific incorporation and combinatorial modification strategies, enabling diverse oligonucleotide designs for both research and therapeutic applications.
Conjugation Options
BiOligo offers a broad range of conjugation strategies for oligonucleotide-antibody, oligonucleotide-peptide, and oligonucleotide-small molecule conjugates, supporting diverse delivery and targeting approaches.
Explore More Conjugation Options
Quality Control
BiOligo offers more than 100 analytical and quality control methods covering:
Identity Testing
Purity Testing
Water Content
Endotoxin Testing
Osmolality
Free Acid Content
Sodium Ion Content
Viscosity Testing
Customized QC packages can be tailored based on modification chemistry, stereochemical requirements, and development stage, ensuring reliable quality support from discovery through preclinical and clinical development.
